GOAT ANTI HUMAN APH-1A Antibody
100ug
MBS224338
597 EUR
Anti-GOAT ANTI HUMAN APH-1A
Caprine ANTI HUMAN APH-1A
Caprinae ANTI Homo sapiens APH-1A
APH-1A
N/A
gamma-secretase subunit APH-1A isoform 1; Gamma-secretase subunit APH-1A; gamma-secretase subunit APH-1A; aph-1alpha; presenilin-stabilization factor; anterior pharynx defective 1 homolog A (C. elegans); Aph-1alpha; Presenilin-stabilization factor
APH-1A
N/A
APH1A; APH1A; APH-1; APH-1A; CGI-78; 6530402N02Rik; PSF; APH-1a
Antibodies
Polyclonal
Polyclonal IgG
Polyclonal antibody
Goat
Human
APH-1A This item specifically recognises human APH-1A (gamma-secretase subunit APH-1A), otherwise known as anterior pharynx defective 1 homolog A, an integral transmembrane protein, and member of the APH-1 family, which is predominantly located in the endoplasmic reticulum and cis-Golgi, and is an essential component of the endoprotease gamma-secretase complex. _x000D__x000D_The gamma-secretase complex, consisting of APH-1 (APH-1A or APH-1B), presenilin-1 or -2 (PSEN1 or PSEN2), nicastrin (NCSTN), and Pen-2 (PEN2), plays a vital role in the evolutionarily conserved Notch signaling pathway, by catalyzing the intramembrane S3 cleavage of ligand-activated Notch receptor proteins (Notch1-4), resulting in the generation and release of an activated NICD fragment, which then translocates to the nucleus and activates the transcription of downstream effector genes. _x000D_
N/A
Purified (Purified IgG - liquid)
IgG concentration 500ug/1000ul
Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
Western Blot (WB), ELISA (EIA)
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Capra aegagrus hircus
anticorps