GOAT ANTI Bcl-2 (N-TERMINAL) Antibody

Name

GOAT ANTI Bcl-2 (N-TERMINAL) Antibody

Size

100ug

Catalog number

MBS224263

Price

608 EUR

More details

Alternative name1

Anti-GOAT ANTI Bcl-2 (N-TERMINAL)

Alternative name2

Caprine ANTI Bcl-2 (N-TERMINAL)

Alternative name3

Caprinae ANTI Bcl-2 (N-TERMINAL)

Alternative name4

Bcl-2

Alternative name5

N/A

Other names

apoptosis regulator Bcl-2 alpha isoform; Apoptosis regulator Bcl-2; apoptosis regulator Bcl-2; protein phosphatase 1, regulatory subunit 50; B-cell CLL/lymphoma 2; N/A

Gene name

Bcl-2

Gene name synonims

N/A

Other gene names

BCL2; BCL2; Bcl-2; PPP1R50; N/A

Category

Antibodies

Clonality

Polyclonal

Immunoglobulin isotype

Polyclonal IgG

Clone

Polyclonal antibody

Host organism

Goat

Species reactivity

Human

Specificity and cross-reactivity

Bcl-2 This item detects an epitope within the N-terminal (NT) region of Bcl-2, a 25kD integral outer mitochondrial membrane protein that blocks apoptotic death in a variety of cell systems. Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability. It inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (apaf-1). Bcl-2 is antiproliferative by facilitating G0 entry._x000D__x000D_Constitutive expression of Bcl-2 is thought to be the cause of follicular lymphoma, also known as type II chronic lymphatic leukaemia. Bcl-2 mutations have also been found in Non-Hodgkin Lymphomas.

Purification method

N/A

Form/Appearance

Purified (Purified IgG - liquid)

Concentration

IgG concentration 500ug/1000ul

Storage and shipping

Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.

Tested for:

Western Blot (WB), ELISA (EIA)

Description

productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.

Advisory

In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Additional description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Properties

If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Latin name

Capra aegagrus hircus

French translation

anticorps