GOAT ANTI MOUSE CD193 (N-TERMINAL) Antibody

Name

GOAT ANTI MOUSE CD193 (N-TERMINAL) Antibody

Size

100ug

Catalog number

MBS223599

Price

531 EUR

More details

Alternative name1

Anti-GOAT ANTI MOUSE CD193 (N-TERMINAL)

Alternative name2

Caprine ANTI Murine CD193 (N-TERMINAL)

Alternative name3

Caprinae ANTI Mus musculus CD193 (N-TERMINAL)

Alternative name4

CD193

Alternative name5

N/A

Other names

probable C-C chemokine receptor type 3; Probable C-C chemokine receptor type 3; probable C-C chemokine receptor type 3; CCR-3; CC-CKR-3; C-C CKR-3; MIP-1 alphaRL2; MIP-1 alpha RL2; CC chemokine receptor 3; chemokine (C-C) receptor 3; chemokine (C-C) receptor 1,-like 2; macrophage inflammatory protein 1-alpha receptor-like 2; chemokine (C-C motif) receptor 3; Macrophage inflammatory protein 1-alpha receptor-like 2

Gene name

CD193

Gene name synonims

N/A

Other gene names

Ccr3; Ccr3; CKR3; Cmkbr3; CC-CKR3; Cmkbr1l2; Cmkbr1l2; Cmkbr3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3

Category

Antibodies

Clonality

Polyclonal

Immunoglobulin isotype

Polyclonal IgG

Clone

Polyclonal antibody

Host organism

Goat

Species reactivity

Mouse

Specificity and cross-reactivity

CD193 This item specifically recognises an epitope within the N-terminal (NT) region of mouse CD193, otherwise known as CCR3 (C-C chemokine receptor type 3), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, expressed by basophils, eosinophils, microglia, Th2 cells and dendritic cells. _x000D__x000D_CD193 acts as a receptor for eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13) and RANTES (CCL5), the former being a chemoattractant for eosinophils and basophils. CD193 is involved in leukocyte chemotaxis and, along with CD191 (CCR1), is implicated as a regulator of T cell and dendritic cell interaction during the process of antigen presentation. CD193 is implicated as an activator of eosinophils in allergic lung disease, and is a useful TH2 cell marker in monitoring immune responses. _x000D_This item is reported as suitable for use in immunocytochemistry on acetone fixed cells.

Purification method

N/A

Form/Appearance

Purified (Purified IgG - liquid)

Concentration

IgG concentration 1.0 mg/ml

Storage and shipping

Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.

Tested for:

Immunohistology - Paraffin (IHC), Western Blot (WB)

Description

productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.

Advisory

In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Additional description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.This is against a protein of mus musculus directed antibody.

Properties

If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Latin name

Capra aegagrus hircus,Mus musculus

Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

French translation

anticorps