GOAT ANTI CHOLESTEROL 24-HYDROXYLASE (C-TERMINAL) Antibody
100ul
MBS222345
486 EUR
Anti-GOAT ANTI CHOLESTEROL 24-HYDROXYLASE (C-TERMINAL)
Caprine ANTI CHOLESTEROL 24-HYDROXYLASE (C-TERMINAL)
Caprinae ANTI CHOLESTEROL 24-HYDROXYLASE (C-TERMINAL)
CHOLESTEROL 24-HYDROXYLASE
N/A
cholesterol 24-hydroxylase; Cholesterol 24-hydroxylase; cholesterol 24-hydroxylase; CH24H; cytochrome P450 46A1; cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase); cytochrome P450, family 46, subfamily A, polypeptide 1; Cytochrome P450 46A1
N/A
N/A
CYP46A1; CYP46A1; CP46; CYP46; CYP46; CH24H
Antibodies
Polyclonal
Polyclonal IgG
Polyclonal antibody
Goat
Human
CHOLESTEROL 24-HYDROXYLASE This item recognises cholesterol 24-hydroxylase (CYP46A1), a 58 kDa member of the Cytochrome P450 family, expressed in the brain. CYP46A1 converts cholesterol into the biologically active oxysterol and 24(S)-hydroxycholesterol, in the first step of the enzymatic degradation of cholesterol in the brain. CYP46A1 is also thought to play a role in the metabolism of neurosteroids and drugs that can cross the blood-brain barrier and are targeted to the central nervous system. _x000D__x000D_P450 enzymes are divided into two groups: steroidogenic and xenobiotic. The latter group is comprised of three families 1, 2 and 3. The xenobiotic p450's are involved in most oxidative drug metabolism. Work in this area is ongoing but studies suggest that all known drug metabolism is mediated by family members: CYP3A, CYP2D6, CYP1A2, CYP2C9/10, CYP2C19 and CYP2E1.
N/A
Serum (Serum - liquid)
N/A
Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
Western Blot (WB), ELISA (EIA)
productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Capra aegagrus hircus
anticorps