GOAT ANTI 4-HYDROXYNONENAL Antibody

Name

GOAT ANTI 4-HYDROXYNONENAL Antibody

Size

100ul

Catalog number

MBS222342

Price

486 EUR

More details

Alternative name1

Anti-GOAT ANTI 4-HYDROXYNONENAL

Alternative name2

Caprine ANTI 4-HYDROXYNONENAL

Alternative name3

Caprinae ANTI 4-HYDROXYNONENAL

Alternative name4

4-HYDROXYNONENAL

Alternative name5

N/A

Other names

N/A

Gene name

4-HYDROXYNONENAL

Gene name synonims

N/A

Other gene names

N/A

Category

Antibodies

Clonality

Polyclonal

Immunoglobulin isotype

Polyclonal IgG

Clone

Polyclonal antibody

Host organism

Goat

Species reactivity

Broad

Specificity and cross-reactivity

4-HYDROXYNONENAL This item recognises 4-hydroxynonenal (HNE). A 65 kDa, highly reactive aldehyde released upon oxidation of omega-6-insaturated fatty acids, often by free radicals. HNE acts to spread and increase the initial effects of free radical events. It binds nucleic acids, phospholipids and sulfhydryl, histidine and lysine groups. These conjugates cause the cytotoxic effects (including cell death) that occur during oxidative stress due to hydrogen peroxide, superoxide, UV, heat and oxidant chemicals. HNE plays a role in the pathogenesis of diseases, stimulating fibrogenesis and inflammation. It is thought to act as a sensor of external stimuli, inducing the stress response by modulating membrane receptors such as Epidermal growth factor receptor or Fas. _x000D__x000D_It is thought that constitutive levels of HNE may be needed for normal cell functions as decreased HNE levels are associated with cell proliferation and increased HNE levels with elevated apoptosis.

Purification method

N/A

Form/Appearance

Serum (Serum - liquid)

Concentration

N/A

Storage and shipping

Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.

Tested for:

Western Blot (WB), ELISA (EIA)

Description

productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.

Advisory

In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.

Additional description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Properties

If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Latin name

Capra aegagrus hircus

French translation

anticorps