Goat anti human Factor VIII related antigen (VWD), Primary Antibodies
1ml
GAHu-FVIII VWD
612 EUR
Goat
Polyclonal
Cardiovascular
Not applicable
NA
Human FVIII procoagulant activity (FVIIIC) is carried by a polypeptide non-covalently bound to a large carrier molecule (unit molecular weight 250 kD) known as the Von Willebrand factor (VWF). FVIII/VWF exists in plasma as a series of polymers with molecular weights > 1.100 kD. FVIIIC is probably formed in the liver, is unstable on storage but sufficiently stable in fresh frozen plasma as cryoprecipitate or FVIII concentrate. VWF is synthesized in megakaryocytes and vascular endothelial cells; it is also present in the alpha-granules and membranes of platelets, binding to specific sites on the activated platelet after its release. It is responsible for platelet adhesion to the vascular subendothelium. FVIIIC, but not VWF is completely consumed during coagulation ad is absent from serum. Polyclonal antisera are raised against FVIII/VWF purified from plasma._x000B__x000B_FreundÍs complete adjuvant is used in the first step of the immunization procedure.
NA
NA
Goat anti human Factor VIII related antigen (VWD), Primary Antibodies philized antiserum is shipped at ambient temperature and may be stored at +4ÁC; prolonged storage at or below -20ÁC. Reconstitute the lyophilized antiserum by adding 1 ml sterile distilled water. Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at +4ÁC, not refrozen, and preferably used the same day. Lyophilized at +4Á C--at least 10 years. Reconstituted at or below -20Á C--3-5 years. Reconstituted at +4Á C--7 days
NA
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.Antigens are peptides or recombinant or native dependent on the production method.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
Capra aegagrus hircus
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.